Melanotan II Peptide (MT-2) – Premium α-MSH Analog for Research Use

🧬 Introduction

Melanotan II peptide (MT-2) is a synthetic analog of the naturally occurring α-Melanocyte Stimulating Hormone (α-MSH). This small cyclic peptide has become a cornerstone in melanocortin receptor and pigmentation research, owing to its unique structure and broad receptor affinity.

In laboratory settings, Melanotan II is used to study melanin production, photoprotective responses, neuroendocrine signaling, and energy metabolism.
Its diverse biological activity makes it one of the most versatile peptides available to researchers exploring dermatological, neurological, and cellular signaling pathways.

At [Your Brand Name], our Melanotan II peptide is manufactured under GMP-like conditions and HPLC-tested to >98% purity, ensuring accuracy and reproducibility for advanced peptide studies.

---

⚙️ Molecular Information

---

🔬 Mechanism of Action

Melanotan II acts primarily as a non-selective agonist of melanocortin receptors—a family of G-protein coupled receptors (MC1R through MC5R). These receptors regulate various physiological functions, including pigmentation, energy balance, and inflammation.

When Melanotan II binds to MC1R, it activates intracellular cAMP pathways, which stimulate melanin synthesis in melanocytes. The resulting increase in melanin production enhances pigmentation, providing a natural photoprotective effect in research models.

Additionally, MC3R and MC4R activation makes Melanotan II a useful tool for studying neuroendocrine signaling, energy regulation, and metabolic control.

Because it interacts with multiple receptor subtypes, MT-2 enables researchers to explore cross-talk between dermatological and neurological systems, expanding its value beyond pigmentation studies.

---

🌿 Scientific Background

The discovery of Melanotan II originated from efforts to synthesize a stable, bioactive analog of α-MSH, a natural peptide hormone responsible for skin pigmentation. Researchers aimed to develop a peptide that maintained the biological potency of α-MSH while improving stability and receptor binding efficiency.

Melanotan II achieved both goals. Its cyclic structure provides greater resistance to enzymatic degradation, extending its activity in vitro and in vivo research models.

Since its development, MT-2 has become a reference compound in studies of:

• Melanin synthesis (melanogenesis)

• Photoprotection and UV response

• DNA repair mechanisms

• Energy metabolism and appetite regulation

• Peptide receptor interactions

Because of its ability to influence multiple signaling cascades, MT-2 remains one of the most frequently cited peptides in melanocortin biology and dermatological pharmacology.

---

💡 Research Applications

1. Melanogenesis and Pigmentation Studies

Melanotan II is a benchmark molecule in research exploring melanin biosynthesis. By stimulating MC1R receptors, it triggers the production of eumelanin, a pigment responsible for darker skin tones and UV protection.
Researchers use MT-2 to model natural tanning pathways and investigate how pigmentation affects cellular oxidative stress and DNA repair.

2. Photoprotection and UV Response

MT-2’s role in melanin synthesis also supports studies of skin photoprotection. In laboratory models, increased melanin levels correlate with improved defense against UV-induced cell damage, making Melanotan II valuable in dermatological and anti-aging research.

3. Melanocortin Receptor Signaling

Melanotan II’s broad receptor affinity allows researchers to examine melanocortin receptor function and signal transduction mechanisms.
Its interaction with MC3R and MC4R receptors has expanded its use to metabolic, appetite, and neuroendocrine studies.

4. Anti-Inflammatory Pathways

Emerging research suggests that melanocortin peptides can modulate inflammatory responses. MT-2 has been utilized in experimental models studying cytokine expression, immune modulation, and oxidative stress.

5. Peptide Therapeutics Development

Due to its receptor specificity and biological stability, Melanotan II serves as a template peptide in pharmaceutical research aimed at developing melanocortin-based therapies.

---

🧪 Quality and Manufacturing Standards

At [Your Brand Name], quality is at the core of our production. Our Melanotan II peptide is:

• Synthesized using solid-phase peptide synthesis (SPPS).

• HPLC-verified for purity and mass spectrometry tested for molecular identity.

• Manufactured under GMP-comparable cleanroom conditions.

• Delivered as a lyophilized powder to preserve integrity.

Each batch includes a Certificate of Analysis (COA) verifying:

• Molecular weight

• Sequence identity

• Purity level

• Endotoxin testing results

This ensures you receive a consistent and reliable research-grade peptide for precise experimental outcomes.

---

⚠️ Important Notice

Melanotan II peptide is sold strictly for laboratory research use only.
It is not intended for human consumption, injection, or cosmetic use.
This product is for qualified professionals conducting scientific or academic research in controlled laboratory environments.

---

🧴 Handling & Storage

To maintain peptide stability:

• Store unreconstituted Melanotan II at −20°C, away from light and moisture.

• Once reconstituted, keep refrigerated and use within 30 days.

• Avoid repeated freeze–thaw cycles.

Proper storage extends the shelf life and preserves purity and structural integrity.

---

🌍 Why Choose Biochem Nova?

Researchers choose Biochem Nova for reliability, purity, and professional support.

✅ What Sets Us Apart:

• ≥98% purity verified by HPLC & MS

• GMP-grade manufacturing

• COA included with every order

• Fast worldwide delivery

• Secure, vacuum-sealed packaging

• Expert research support

Our peptides are trusted by universities, research centers, and pharmaceutical laboratories around the world.

---

🧾 Product Summary

• Name: Melanotan II (MT-2)

• Type: Synthetic α-MSH analog

• Purity: ≥98%

• Form: Lyophilized powder

• Intended Use: Research only

• Storage: −20°C, dark and dry environment

• Packaging: Light-resistant, vacuum-sealed vial

• Testing: HPLC and MS verified

---

❓ Frequently Asked Questions

1. What is Melanotan II peptide?

Melanotan II is a synthetic peptide analog of α-MSH used in research related to pigmentation, melanin production, receptor signaling, and photoprotection.

2. How pure is your Melanotan II peptide?

Our MT-2 peptide is ≥98% pure, confirmed through high-performance liquid chromatography (HPLC) and mass spectrometry analysis.

3. Is Melanotan II for human use?

No. Melanotan II is strictly for laboratory and scientific research. It is not approved for human or animal use.

4. What are common research applications?

Researchers use Melanotan II for studies involving melanin production, UV protection, melanocortin receptor signaling, and peptide hormone activity.

5. How should Melanotan II be stored?

Store the lyophilized peptide at −20°C, away from light and moisture. Reconstituted peptide should be refrigerated and used promptly.

---

🚀 Order Melanotan II Peptide

Enhance your research with precision, purity, and performance.
Order Melanotan II peptide (MT-2) today from [Your Brand Name] and experience unmatched laboratory quality.

👉 [Buy Melanotan II Peptide Now] | [Request COA or Bulk Quote]